A new approach to making existing alternatives more accurate

For many years, scientists have used non-animal test tube experiments with mammal cells and bacteria to test how potentially harmful ingredients interact with DNA. However, these test tube or in vitro experiments often create false alerts, leading to unnecessary follow-up research with animals for ingredients that aren't actually harmful.

In response, P&G — along with Cosmetics Europe, the European Trade Association for cosmetics manufacturers — has developed a new cutting edge test using artificial skin to act as a direct replacement for animal studies. This 3D skin model, which is currently in the validation stage, uses three-dimensional human skin generated from cells donated by human volunteers.

"At P&G, we hope this work, like all of our other research of on alternatives, will transform safety tests and help to eliminate research involving animals completely."

Stefan Pfuhler, PhD, Research Fellow

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